Simple, what is your favorite webcomic? The ones I check daily are:

Ctrl+Alt+Del
A whacky comic series about two roommates living together. Antics include a robot built from an Xbox, a nutty chef named Brian, and a dude who lives with a penguin. Game and tech related humor dominate this strip.

Cyanide and Happiness
Nothing is sacred or off limits. AIDS, cancer, necrophilia, pedophilia, it's all here in stick character form to create one of the funniest and offensive comics to date. Simply put, it's epic.

Questionable Content
A more realistic comic with an indie scene atmosphere. The strip focuses on the drama between a group of friends but don't let that turn you away! The humor is great and will always leave you with a laugh while the story itself is not without heart.

So what are your picks?

I read CAD and Cyanide and recently read through xkcd thanks to Hime.

xkcd - A webcomic of romance, sarcasm, math, and language - By Randall Munroe

There are tons of webcomics that I read regularly or just plain love:

Penny Arcade

PvP

VG Cats

The Adventures of Dr. McNinja

Rob and Elliot

Scary Go Round

These ones don't update that much, but when they do they are awesome:

Gone with the Blastwave

The Perry Bible Fellowship

Penny Arcade
PvP
Three Panel Soul (same guys who did Mac Hall)
AppleGeeks
VG Cats
Rob and Elliot

Don't usually follow the ones with big storylines. I tend to go for the gags more than anything else.

VG Cats - Updated Mondays

Looking For Group

I found this to be pretty awesome:



EXTRALIFE - Web comic for geeks, gamers, and stuff like that

CAD is the only one I read regularly. I can't stand PA, and keep forgetting about XKCD.

M.

Cyanide and Happiness

VG Cats

I'm not much of a webcomic reader though

San: Three Kingdoms Comic

A nice parody of the Three Kingdoms Dynasty with the design of Koei's Dynasty Warriors :D

I find it surprising that only one person has listed The Adventures of Dr. McNinja.

Anyway...

Order of the Stick

The Adventures of Dr. McNinja

Least I Could Do

Looking For Group

Fanboys

Horribleville

Three Panel Soul

A number of things you'd find on Fireball20xl.com

Girly

No Need For Bushido

Flipside

I have more webcomics in my bookmarks, but those are the ones I check most often.