If you have played the first one you will know what it is, and yes the second one is coming out soon. I can't wait for this to come out, I will probably pre-order it myself, it has been a long time in the making and should be good, and also with the release it should get the community busy again.

For those who don't know what it is, should check it out: Natural Selection 2 Promo Site - View teaser

And if you want to play and give it a shot, try playing the first one and get a feel for the game play, it is a fps and strategy game in one. You will only be able to play the first one if you have half life on steam.